Correlations between apoe4 allele and regional amyloid and tau burdens in cognitively normal older individuals

HIGHLIGHTS

  • who: Yun Jeong Hong from the DepartmentCatholic University have published the paper: Correlations between APOE4 allele and regional amyloid and tau burdens in cognitively normal older individuals, in the Journal: Scientific Reports Scientific Reports
  • what: In preclinical AD, APOE4 carrier status had robust correlations with increased amyloid burden in diffuse cortical areas, while, it had weaker and mixed correlations with the regional tau burden and did not have correlation with the cortical thickness.
  • how: The clinical characteristics including neuropsychological tests results and CSF biomarker data were obtained from the ADNI 3 files. Full . . .

     

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