Dna methylation analysis of normal colon organoids from familial adenomatous polyposis patients reveals novel insight into colon cancer development

HIGHLIGHTS

  • who: Matthew A. Devall from the Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA have published the research: DNA methylation analysis of normal colon organoids from familial adenomatous polyposis patients reveals novel insight into colon cancer development, in the Journal: (JOURNAL)
  • what: The authors provide evidence suggesting that some of these DMRs led to significant differences in gene expression of adjacent genes using quantitative PCR. The studies provide potential insight into early tumorigenic events in FAP that may also be relevant to the development of nonhereditary forms of CRC. All healthy subjects . . .

     

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