Immunodeficiency syndromes differentially impact the functional profile of sars-cov-2-specific t cells elicited by mrna vaccination

HIGHLIGHTS

  • who: Yu Gao from the Department Karolinska University for Immunology, La Jolla, CA, USA have published the paper: Immunodeficiency syndromes differentially impact the functional profile of SARS-CoV-2-specific T cells elicited by mRNA vaccination, in the Journal: (JOURNAL) of September/13,/2022
  • what: The authors show that mRNA_vaccines induce a broad spectrum of highly active antiviral T_cell clonotypes that aid in explaining how these vaccines generate protective responses against severe COVID-19 in healthy individuals.
  • how: Next using the marker genes for each cluster the authors applied gene set enrichment analysis . . .

     

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