A mycobacterium avium subsp. paratuberculosis rela deletion mutant and a 35 kda major membrane protein elicit development of cytotoxic t lymphocytes with ability to kill intracellular bacteria

HIGHLIGHTS

• who: Gaber S. Abdellrazeq from the Eight Holstein steers were obtained from the Map free Washington State University (WSU) dairy herd from , to In the first phase of the study, two of the steers were vaccinated with the ΔMap/relA mutant and maintained as a source of blood to characterize cell responses elicited by ΔMap/relA and MMP. Two additional age-matched naïve steers were maintained as controls. In the second phase of the study, four additional unvaccinated naïve steers were used as a source of blood to conduct the ex vivo studies on the . . .
  

   

  

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