Regulator of cullins-1 (roc1) negatively regulates the gli2 regulator sufu to activate the hedgehog pathway in bladder cancer

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  • who: W. Wang from the (UNIVERSITY) have published the research work: Regulator of cullins-1 (ROC1) negatively regulates the Gli2 regulator SUFU to activate the hedgehog pathway in bladder cancer, in the Journal: (JOURNAL)
  • what: This study demonstrated that dysregulation of the axis plays an important role in progression and that targeting expression is warranted in further investigations as a novel strategy for the future control of As accumulating evidence suggests an essential role of hedgehog signaling in tumor cell proliferation , in this study, the authors explored the underlying molecular mechanisms by which ROC1 regulates . . .

     

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