Sex differences in kidney function and metabolism assessed using hyperpolarized [1- c]pyruvate interleaved spectroscopy and nonspecific imaging

HIGHLIGHTS

  • who: Yibo Wen and colleagues from the MR Research Centre, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark have published the research: Sex Differences in Kidney Function and Metabolism Assessed Using Hyperpolarized [1- C]Pyruvate Interleaved Spectroscopy and Nonspecific Imaging, in the Journal: (JOURNAL)
  • what: This study shows an existing metabolic difference between kidneys in age-matched male and female rats which indicates that sex differences need to be considered when performing animal experiments. Regardless, both aged-matched and dose-matched males showed similar increased conversion of pyruvate to lactate compared with the female rats . . .

     

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