HIGHLIGHTS
- who: Jennifer L Asimit from the C EU have published the research: A two-stage inter-rater approach for enrichment testing of variants associated with multiple traits, in the Journal: (JOURNAL)
- what: The overall purpose of the proposed method, corrected overlap and marginal enrichment test (COMET), is to determine whether agreement (overlap) between the verdicts of association between a SNP and a phenotype can be related to SNPspecific (eg, functional annotation) or trait × SNP-specific characteristics, such as membership of known biological pathways. Analogous to comparing measurements taken by raters on the same individuals, the . . .
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