Design and in vitro evaluation of layer by layer sirna nanovectors targeting breast tumor initiating cells

HIGHLIGHTS

• who: Hamsa Jaganathan and collaborators from the Research Institute, Houston, Texas, United States of America have published the Article: Design and In Vitro Evaluation of Layer by Layer siRNA Nanovectors Targeting Breast Tumor Initiating Cells, in the Journal: PLOS ONE | www.plosone.org of February/15,/2014
• what: In this study layer by layer (LBL) small interfering RNA (siRNA) nanovectors (SNVs) were designed to target breast TICs. The data from this study show for the first time that SNVs in LBL assembly effectively delivers STAT3 siRNA and inhibit the growth of breast TICs in vitro . . .
  

   

  

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