Engineering hiv-1-resistant t-cells from short-hairpin rna-expressing hematopoietic stem/progenitor cells in humanized blt mice

HIGHLIGHTS

• who: Gene-Errol E. Ringpis et al. from the Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CaliforniaEditor: Roberto FSpeck, University Hospital Zurich, Switzerland have published the Article: Engineering HIV-1-Resistant T-Cells from Short-Hairpin RNA-Expressing Hematopoietic Stem/Progenitor Cells in Humanized BLT Mice, in the Journal: PLOS ONE | www.plosone.org of December/31,/2012
• what: The authors report that human CD4+ T-cells derived from transplanted HSPC engineered to co-express shRNAs targeting CCR5 and HIV-1 LTR . . .
  

   

  

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