HIGHLIGHTS
- who: A Targeted Library Screen et al. from the Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Department of Chemistry and Center have published the research: A Targeted Library Screen Reveals a New Inhibitor Scaffold for Protein Kinase D, in the Journal: PLOS ONE | www.plosone.org of September/18,/2012
- what: The authors evaluated of 235 small organic kinase inhibitors for PKD1 inhibitory activity at single concentration. This approach provided both ATP-competitive active_site, and noncompetitive, presumably allosteric_site inhibitors (Fig 1). The study has identified a novel . . .
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