Scaffold pore curvature influences msc fate through differential cellular organization and yap/taz activity

HIGHLIGHTS

  • who: W. Benton Swanson and collaborators from the Department of Biologic and Materials Science, Division of Prosthodontics, University of Michigan School Ann Arbor, MI, USA have published the research: Scaffold Pore Curvature Influences MSC Fate through Differential Cellular Organization and YAP/TAZ Activity, in the Journal: (JOURNAL) of 15/Dec/2021
  • what: The authors demonstrate that principle directly influences nuclear aspect and cell aggregation in vitro. pores with a sufficiently low degree of principle enables cell differentiation; pharmacologic inhibition of actin cytoskeleton polymerization in these scaffolds decreased differentiation indicating a critical role of the cytoskeleton . . .

     

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