HIGHLIGHTS
- who: Jérôme Cartry and collaborators from the Laboratoire University of have published the article: Neofunctionalization in Vertebrates: The Example of Retinoic Acid Receptors, in the Journal: (JOURNAL)
- what: The authors have investigated how gene duplication has affected both the expression and the ligand-binding specificity of retinoic acid receptors (RARs) which play a major role in chordate embryonic development. To decipher how gene duplications affected the ligand binding function, in this work the authors studied RARs of several chordates as well as a reconstructed RAR representing the hypothetical sequence present in the ancestor . . .
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