HIGHLIGHTS
- who: Emilie Vassal-Stermann from the Université University of have published the Article: CryoEM structure of adenovirus type 3 fibre with desmoglein 2 shows an unusual mode of receptor engagement, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- what: The authors report the structure of HAd3 fibre knob (HAd3K) in complex with one and two molecules of the DSG2 receptor. While the structure of 1:1 (fibre knob:receptor) has never been reported for other protein receptors prior to this study, HAd37K binding to the GD1a glycan exhibits a 1:1 binding mode.
SUMMARY . . .
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