HIGHLIGHTS
- who: Sydney P. Craig III from the (UNIVERSITY) have published the paper: Purine Phosphoribosyltransferases*, in the Journal: (JOURNAL)
- what: Crystal_Structures of Purine PRTs For this review, residue numbers refer to the positions of amino_acids in the human HPRT, the bacterial XPRT, or the leishmanial APRT, as these enzymes were the first of their class for which crystal_structures were reported .
SUMMARY
The C-terminal ends of the  sheets of the core domains of purine PRTs form the floor of the active_sites of these enzymes. A poorly conserved hood domain contributes residues that . . .
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