Correcting the mean-variance dependency for differential variability testing using single-cell rna sequencing data

HIGHLIGHTS

  • who: Nils Eling from the Molecular Biology Laboratory Cambridge , SD, UK University of have published the research work: Correcting the Mean-Variance Dependency for Differential Variability Testing Using Single-Cell RNA Sequencing Data, in the Journal: (JOURNAL) of September/26,/2018
  • what: As in Vallejos et_al , the authors focus on biological over-dispersion as a proxy for transcriptional heterogeneity. As expected, this analysis shows an overall increase in variability in the mixed population. The authors focus on samples collected 2, 4, and 7 days post malaria infection, for which more than 50 cells are available . . .

     

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