Membrane tension orchestrates rear retraction in matrix-directed cell migration

HIGHLIGHTS

  • who: Joseph H.R. Hetmanski from the Centre University of UK have published the paper: Membrane Tension Orchestrates Rear Retraction in Matrix-Directed Cell Migration, in the Journal: (JOURNAL) of November/18,/2019
  • what: Using Flipper-TR, the authors show that the in-plane membrane tension is reduced at the rear of cells moving in 3D .
  • how: In the absence of a chemotactic gradient the authors hypothesized that the direction of migration along matrix fibrils could be determined by the physical properties of the matrix.

SUMMARY

    The plasma_membrane is . . .

     

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