Identification of potential drug targets in cancer signaling pathways using stochastic logical models

HIGHLIGHTS

  • who: Peican Zhu from the DepartmentUniversity of Alberta, Edmonton, AB T G , Canada have published the research: Identification of Potential Drug Targets in Cancer Signaling Pathways using Stochastic Logical Models, in the Journal: Scientific Reports Scientific Reports
  • what: In this work, hence, cell death is determined by a weighted combination of the three sub-pathways.
  • how: A targeting strategy is introduced to implement a ‘dysfunction' of a gene node. The evaluation accuracy improves with sequence length but an accurate result can be obtained by using a reasonable sequence length. In this model each . . .

     

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