Type iv secretion of helicobacter pylori caga into oral epithelial cells is prevented by the absence of ceacam receptor expression

HIGHLIGHTS

• who: Nicole Tegtmeyer from the CEACAM-independent have published the research work: Type IV secretion of Helicobacter pylori CagA into oral epithelial cells is prevented by the absence of CEACAM receptor expression, in the Journal: (JOURNAL)
• what: The authors investigated the interactions between H. pylori and three oral epithelial_cell lines (HN, CAL-27 and BHY), which confirmed the dependence on CEACAM receptors for CagA intracellular delivery. The authors propose that a yet unknown non-canonical T4SS-independent NF-κB pathway is induced in infected HN cells.
• how: Most of those observations were made . . .
  

   

  

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