Glp-1 – oestrogen attenuates hyperphagia and protects from beta cell failure in diabetes-prone new zealand obese (nzo) mice

HIGHLIGHTS

• who: Pomc and colleagues from the Department of Experimental Diabetology, German Institute of, Nuthetal, Germany Technical University Munich, Munich, Germany have published the research: GLP-1 - oestrogen attenuates hyperphagia and protects from beta cell failure in diabetes-prone New Zealand obese (NZO) mice, in the Journal: (JOURNAL)
• what: The aim of this study was to compare the effects of and during beta cell failure under glucolipotoxic conditions.
• how: The data are in line with these published observations and suggest that reduced caloric intake via pro-opiomelanocortin (POMC) activation is the major mechanism leading . . .
  

   

  

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