Nuclear defects in skeletal muscle from a dynamin 2-linked centronuclear myopathy mouse model

HIGHLIGHTS

  • who: Anaamp#x000EF and s Fongy from the (UNIVERSITY) have published the article: Nuclear defects in skeletal muscle from a Dynamin 2-linked centronuclear myopathy mouse model, in the Journal: Scientific Reports Scientific Reports of 14/Nov/2018
  • what: The authors demonstrate that number of myonuclei and satellite cell content are impacted in the KI-Dnm2 mice.
  • how: The results showed that similarly to WT fibres the size of HTZ fibres remains linked to the number of the nuclei suggesting that hypotrophy is at least partially due to a lower number of myonuclei . . .

     

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