Jhi-21 plays a role in drosophila insulin-like peptide release from larval ipcs via leucine transport

HIGHLIGHTS

  • who: Anna B. Ziegler from the (UNIVERSITY) have published the paper: JhI-21 plays a role in Drosophila insulin-like peptide release from larval IPCs via leucine transport, in the Journal: (JOURNAL) of 15/08/2017
  • what: The authors show that a second leucine transporter, JhI-21, of the same family is additionally necessary for proper leucine sensing in the IPCs. Using calcium imaging and ex-vivo cultured brains the authors show that knockdown of JhI-21 in IPCs causes malfunction of these cells: they are no longer able to sense dietary leucine or to . . .

     

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