A universal influenza vaccine can lead to disease exacerbation or viral control depending on delivery strategies

HIGHLIGHTS

  • who: Isabelle Schwartz-Cornil from the Argentina Argentina Argentina have published the research work: A Universal Influenza Vaccine Can Lead to Disease Exacerbation or Viral Control Depending on Delivery Strategies, in the Journal: (JOURNAL)
  • what: The authors assessed whether the delivery of the three conserved IAV AG HA2, M2e, and NP by DC targeting in different anatomical sites could shape the immune_response toward protective immunity and avoid disease exacerbation in pigs. Whereas the authors aimed at preventing this detrimental effect with DC targeting, on the contrary the authors found that CD11c-targeting promoted disease exacerbation . . .

     

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