Mauve/lyst limits fusion of lysosome-related organelles and promotes centrosomal recruitment of microtubule nucleating proteins

HIGHLIGHTS

  • who: Ramona Lattao from the University of Genetics, Downing Street, Cambridge CB EH, UK have published the research work: Mauve/LYST limits fusion of lysosome-related organelles and promotes centrosomal recruitment of microtubule nucleating proteins, in the Journal: (JOURNAL)
  • what: The authors show that embryos derived from mutant mv females have enlarged YGs that fuse with LDs, and this can be reverted by reducing Rab5 activity. mv-derived embryos also show compromised MT nucleation leading to defects in the embryo's mitotic cycles and cytoskeletal organization. The study has identified a requirement for Mauve, the . . .

     

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