Gag-protease coevolution analyses define novel structural surfaces in the hiv-1 matrix and capsid involved in resistance to protease inhibitors

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  • who: Francisco M Codoamp#x000F1 and er from the Lifesequencing SL, Paterna, Spain Universidad Catolica de Valencia, Valencia, Spain. AIDS Research Institute have published the research work: Gag-protease coevolution analyses define novel structural surfaces in the HIV-1 matrix and capsid involved in resistance to Protease Inhibitors, in the Journal: Scientific Reports Scientific Reports of 10/01/2017
  • what: Using this approach, the authors determined hotspots of protease coevolution under pressure from PIs in Gag structural proteins, mainly in the matrix, but also in the capsid. The study provides novel insights into the contribution . . .

     

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