Cardiotoxicity of chimeric antigen receptor t-cell (car-t) therapy: pathophysiology, clinical implications, and echocardiographic assessment

HIGHLIGHTS

  • who: Antonio Nenna et al. from the Saint-Denis, Paris, France have published the research: Cardiotoxicity of Chimeric Antigen Receptor T-Cell (CAR-T) Therapy: Pathophysiology, Clinical Implications, and Echocardiographic Assessment, in the Journal: (JOURNAL) of 26/05/2022
  • what: Considering the clinical benefits of specific anti-IL-6 treatment, recent studies focused on other relevant cytokines involved in CRS.
  • future: Reporting remains heterogeneous warranting a standardization of methods and endpoints to allow a detailed comparison in future studies . This review aims to summarize the pathophysiology clinical and of CAR-T-related cardiotoxicity . . .

     

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