Genetically diverse mouse platform to xenograft cancer cells

HIGHLIGHTS

  • who: from the (UNIVERSITY) have published the research: Genetically diverse mouse platform to xenograft cancer cells, in the Journal: (JOURNAL) of 10/01/2022
  • what: This led to the National Institutes of Health (NIH), in June 2021, to cite a lack of genetic diversity in preclinical studies as one of the main reasons for failure of clinical trials (ACD Working Group on Enhancing Rigor, Transparency, and Translatability in Animal Research; https://acd.od.nih.gov/documents/presentations/ 06112021_RR-AR%20Report.pdf ). The authors show, using the panel of three to five host strains, that the . . .

     

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