Integrative genomic and transcriptomic analyses illuminate the ontology of her2-low breast carcinomas

HIGHLIGHTS

  • who: Enrico Berrino from the Department of Medical Sciences, University of Turin, Turin, Italy have published the paper: Integrative genomic and transcriptomic analyses illuminate the ontology of HER2-low breast carcinomas, in the Journal: (JOURNAL)
  • what: The authors aimed at characterizing HLBCs at the molecular level to assess whether they represent a distinct entity. The authors show that HER2-low breast carcinomas harbor a constellation of somatic mutations that shows significant differences compared to HER2-positive and HER2negative BCs. The study provides an overview of the landscape of potentially targetable genetic alterations for HER2-low . . .

     

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