Synthesis of n-substituted iminosugar c-glycosides and evaluation as promising -glucosidase inhibitors

HIGHLIGHTS

• who: Haibo Wang and colleagues from the Chengdu, China University of Chinese Academy of Sciences, Beijing, China have published the research: Synthesis of N-Substituted Iminosugar C-Glycosides and Evaluation as Promising -Glucosidase Inhibitors, in the Journal: Molecules 2022, 5517 of 28/Dec/2021
• what: As a part of the continuing interest in the synthesis of novel iminosugars and their α-glucosidase inhibition, the authors report a library of N-substituted iminosugar C-glycosides and their structure-activity relationships against α-glucosidase.
• how: The same result was obtained when introducing electron-donating groups as CH3 . . .
  

   

  

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