Modification of alternative splicing of bcl-x pre-mrna in prostate and breast cancer cells

HIGHLIGHTS

• who: Danielle R. Mercatante from the (UNIVERSITY) have published the research work: Modification of Alternative Splicing of Bcl-x Pre-mRNA in Prostate and Breast Cancer Cells, in the Journal: (JOURNAL) of October/11,/2000
• what: The authors show here that this shift in splicing could indeed be accomplished and that it induced apoptotic markers in the prostate cancer cell line PC-3. This analysis showed a time-dependent decrease in Bcl-xL protein (Fig 3, upper panel, lanes 2-5) and an increase in Bcl-xS protein (lower panel, lanes 2-5) in cells . . .
  

   

  

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