HIGHLIGHTS
- who: Franziska E. Uhl from the University Belfast, United Kingdom have published the article: Cystic fibrosis transmembrane regulator correction attenuates heart failure-induced lung inflammation, in the Journal: (JOURNAL)
- what: This model shows stable cardiac injury 6 weeks after MI . In accordance, the authors show that pharmacological increase of CFTR expression, which increases the proportion of CFTR+ cells in the lung, diminishes the HFassociated elevation of classically-activated non-alveolar macrophages, induces the increase of an alternative macrophage polarization, and normalizes vessel wall thickness within the lungs of HF mice. In the experiments , the authors . . .
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