Homeostatic regulation of extracellular signal-regulated kinase 1/2 activity and axonal kv7.3 expression by prolonged blockade of hippocampal neuronal activity

HIGHLIGHTS

  • who: Hee Jung Chung from the University of Illinois at Chicago, United States have published the paper: Homeostatic regulation of extracellular signal-regulated kinase 1/2 activity and axonal Kv7.3 expression by prolonged blockade of hippocampal neuronal activity, in the Journal: (JOURNAL)
  • what: The authors investigated if homeostatic scaling of intrinsic excitability involves the downregulation of Kv 7 channels at the AIS via a reduction in ERK1/2 signaling. For image analysis, the authors focused on the ankyrin-G-positive segment of an axon that originates from the soma. The authors propose that the . . .

     

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