The egfr/erbb inhibitor neratinib modifies the neutrophil phosphoproteome and promotes apoptosis and clearance by airway macrophages

HIGHLIGHTS

  • who: Kimberly D. Herman from the Universitéde Montréal, Canada Setsunan University, Japan have published the research: The EGFR/ErbB inhibitor neratinib modifies the neutrophil phosphoproteome and promotes apoptosis and clearance by airway macrophages, in the Journal: (JOURNAL)
  • what: To determine whether neratinib treatment altered the damage to the lung tissue observed in this model, histological analysis was carried out on lung tissue slices . The authors show that neratinib, an ErbB inhibitor used to treat breast cancer, may be able to reduce acute inflammation in the lungs, by reducing the number of neutrophil corpses . . .

     

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