Structural requirements for the antifungal activities of natural drimane sesquiterpenes and analogues,

HIGHLIGHTS

  • who: Marcos Derita 1 et al. from the Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha, Rosario, Argentina have published the paper: Structural Requirements for the Antifungal Activities of Natural Drimane Sesquiterpenes and Analogues,, in the Journal: Molecules 2013, 18, 2029-2051 of 18/Dec/2012
  • what: This work showed that the 7,8-double bond in the drimane scheleton should be considered one of the necessary structural features for antifungal activity, either alone as in compounds 3, 5-10 and 14, or as part of a C-8 α,β-unsaturated . . .

     

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