HIGHLIGHTS
- who: Andrea Kosta from the Shenzhen Institute of Advanced Technology (SIAT) (CAS), China University of Genoa, Italy have published the paper: GAS6/TAM signaling pathway controls MICA expression in multiple myeloma cells, in the Journal: (JOURNAL)
- what: Based on these observations, the authors propose a role for NF-kB as a direct positive regulator of MICA promoter in MM cells. The authors provide first evidence that surface MICA expression is regulated by GAS6/TAM pathway in MM cells. The authors demonstrate that: GAS6/AXL and MERTK signaling, in a cell-autonomous way, sustains MICA expression . . .
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