Thioredoxin as a molecular target of cyclopentenone prostaglandins*

HIGHLIGHTS

• who: Takahiro Shibata from the nisms by which, d-, induces intracellular oxidative stress and neuronal cell deathAcknowledgments-We thank Dr. Takeshi Kumagai (Nagoya University) for helpful advice. have published the article: Thioredoxin as a Molecular Target of Cyclopentenone Prostaglandins*, in the Journal: (JOURNAL) of April/21,/2003
• what: In the present study, based on the observation that the electrophilic center of 15d-PGJ2 was involved in the pro-oxidant effect, the authors investigated the role of thioredoxin 1 (Trx), an endogenous redox regulator, against 15d-PGJ2-induced oxidative cell injury.
• how: The authors . . .
  

   

  

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