Cholesterol is not crucial for the existence of microdomains in kidney brush-border membrane models*

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  • who: Pierre Emmanuel Milhiet from the (UNIVERSITY) have published the Article: Cholesterol Is Not Crucial for the Existence of Microdomains in Kidney Brush-border Membrane Models*, in the Journal: (JOURNAL) of November/13,/2001
  • what: In this study, the thermotropic behavior and the topology of bilayers made of a phosphatidylcholine/sphingomyelin mixture, which mimicks the lipid composition of the external leaflet of renal brush-border membranes, were examined by differential scanning calorimetry and atomic force microscopy. Using a lipid bilayer model close to biological membranes, the authors provide here strong evidence that, in cells rich . . .

     

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