HIGHLIGHTS
- who: Alana M. Thackray and collaborators from the Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge , ES, UK. have published the paper: Transcriptional signature of prion-induced neurotoxicity in a Drosophila model of transmissible mammalian prion disease, in the Journal: (JOURNAL) of 28/02/2020
- what: The analysis has revealed that during the early phase of prion infection in PrP(GPI) transgenic Drosophila, there was up-regulation of genes associated with cell cycle activity and DNA damage repair, followed by down-regulation of the protein synthesis regulation pathways eIF2 and mTOR (mechanistic target . . .
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