Promoting drp1-mediated mitochondrial fission in midlife prolongs healthy lifespan of drosophila melanogaster

HIGHLIGHTS

• who: Anil Rana from the University of have published the Article: Promoting Drp1-mediated mitochondrial fission in midlife prolongs healthy lifespan of Drosophila melanogaster, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors show that inducing Drp1-mediated mitochondrial fission, in midlife, increases lifespan and improves multiple markers of health in aged Drosophila. Remarkably, the authors show that a transient induction of Drp1, for 7 days, in midlife is sufficient to prolong lifespan. The authors show that disruption of Atg1, a core autophagy gene, inhibits the anti-aging, prolongevity effects of midlife Drp1 induction . . .
  

   

  

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