The dpp-4 inhibitor vildagliptin impacts the gut microbiota and prevents disruption of intestinal homeostasis induced by a western diet in mice

HIGHLIGHTS

• who: Marta Olivares from the Institute, Université catholique de Louvain, avEMounier, Productos Lácteos de Asturias (IPLA-CSIC), Villaviciosa, Spain have published the article: The DPP-4 inhibitor vildagliptin impacts the gut microbiota and prevents disruption of intestinal homeostasis induced by a Western diet in mice, in the Journal: (JOURNAL)
• what: The authors propose that vildagliptin exerts beneficial effects at the intestinal level in association with modulation of gut microbiota with consequences for hepatic immunity. Consistent with this, the authors show that vildagliptin decreased DPP-4 activity in the liver (ESM Fig 9). The authors . . .
  

   

  

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