Adar1-mediated rna editing is a novel oncogenic process in thyroid cancer and regulates mir-200 activity

HIGHLIGHTS

• who: Julia Ramírez-Moya from the Instituto de Investigaciones Biomédicas "Alberto Sols" have published the research work: ADAR1-mediated RNA editing is a novel oncogenic process in thyroid cancer and regulates miR-200 activity, in the Journal: (JOURNAL)
• what: The authors show that ADAR1 expression and consequent RNA editing alters thyroid cancer cell aggressiveness through its effects on proliferation, invasion, migration, and 3D growth in_vitro, and tumor growth in_vivo. The authors relate the main thyroid cancer signaling pathways to ADAR1 isoform levels, and the authors provide evidence that pharmacological inhibition of Ato-I . . .
  

   

  

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