HIGHLIGHTS
- who: Biology et al. from the Department of Internal Medicine I, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany, University have published the research: Insights Into Bone Marrow Niche Stability: An Adhesion and Metabolism Route, in the Journal: (JOURNAL)
- what: The authors propose that this results in reduced integrinmediated adhesion in malignancies.
- how: This review describes how various hematopoietic and nonhematopoietic cell types interact within the normal and malignant microenvironment.
SUMMARY
The endosteal niche promotes HSC (Lin- CD34+ CD38-) quiescence due to its unique composition (Nilsson . . .
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