HIGHLIGHTS
- who: Laura Laprell from the (UNIVERSITY) have published the research: Optical control of NMDA receptors with a diffusible photoswitch, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 27/08/2015
- what: The authors show that ATG is the first diffusible PCL that can be precisely controlled with two-photon excitation (740 nm). The authors show that ATG photoswitching and lightdependent NMDAR activation can be achieved with a monochromator, LEDs or laser light source. The authors demonstrate, for the first time, the fundamental ability to switch ‘off' channel agonism, thereby speeding the decay of NMDAR currents . . .
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