Differential meta-analysis of rna-seq data from multiple studies

HIGHLIGHTS

  • who: Rau et_al BMC Bioinformatics and collaborators from the (UNIVERSITY) have published the Article: Differential meta-analysis of RNA-seq data from multiple studies, in the Journal: (JOURNAL)
  • what: The authors demonstrate how p-value combination techniques previously used for microarray meta-analyses can be used for the differential analysis of RNA-seq data from multiple related studies. The authors compare these two methods to the results of independent per-study analyses and a negative binomial generalized linear model (GLM) with a fixed study effect as implemented in the DESeq Bioconductor package . The authors propose . . .

     

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