HIGHLIGHTS
- who: Stefano Testa and colleagues from the Department of Medicine, Stanford University, Stanford, CA, USA have published the paper: A Retrospective Comparative Analysis of Outcomes and Prognostic Factors in Adult and Pediatric Patients with Osteosarcoma, in the Journal: (JOURNAL)
- what: In this study adding methotrexate to a combination of doxorubicin and cisplatin did not correlate with better outcomes for adult patients with osteosarcoma, questioning the benefit of methotrexate-based chemotherapy in young adults.
- future: Given the emerging evidence that high-dose methotrexate may not add significantly to the efficacy of AP future studies . . .
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