Antibiotic-related gut dysbiosis induces lung immunodepression and worsens lung infection in mice

HIGHLIGHTS

  • who: Rodrigue Dessein from the UnivLille, CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, University Lille, Lille, France have published the research work: Antibiotic-related gut dysbiosis induces lung immunodepression and worsens lung infection in mice, in the Journal: (JOURNAL)
  • what: The authors aim to determine the effects of antibioticinduced gut dysbiosis, without lung dysbiosis, on outcomes in a non-lethal murine model of acute P. aeruginosa lung infection and the underlying immune alterations to manage side effects of antibiotics. In previous studies in which antibiotic-induced gut dysbiosis was shown to worsen bacterial pneumonia . . .

     

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