Mirnome profiling and functional analysis reveal involvement of hsa-mir-1246 in colon adenoma-carcinoma transition by targeting axin2 and cftr

HIGHLIGHTS

  • who: Rokas Lukosevicius and collaborators from the Institute for Digestive Research, Academy of Medicine, Lithuanian University of Health Sciences have published the article: miRNome Profiling and Functional Analysis Reveal Involvement of hsa-miR-1246 in Colon Adenoma-Carcinoma Transition by Targeting AXIN2 and CFTR, in the Journal: (JOURNAL)
  • what: In this study by employing small RNA-seq profiling of colon biopsy samples the authors described differentially expressed miRNAs and their isoforms in the adenoma-carcinoma transition. The analysis showed three clearly resolved clusters concordant with CRC, AP, and HC groups. This study has certain limitations . . .

     

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