Structure and function of the transketolase from mycobacterium tuberculosis and comparison with the human enzyme

HIGHLIGHTS

• who: Mycobacterium tuberculosis et al. from the University of Birmingham, Edgbaston, Birmingham, TT, UK have published the article: Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme, in the Journal: (JOURNAL) of 09/09/2022
• what: As the first step in this process, the authors report here the structural and functional studies of the TKT enzyme from M. tuberculosis (TBTKT), encoded by gene rv1449c, and discuss structural differences between the human, yeast and bacterial homologues.
• how: Two inhibitors of the human TKT were tested for inhibitory activity . . .
  

   

  

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