Extracellular bmp antagonists, multifaceted orchestrators in the tumor and its microenvironment

HIGHLIGHTS

  • who: Sarah Ouahoud and colleagues from the Department of Gastroenterology and Hepatology, Leiden University Medical Centre, ZA Leiden have published the research work: Extracellular BMP Antagonists, Multifaceted Orchestrators in the Tumor and Its Microenvironment, in the Journal: (JOURNAL)

SUMMARY

    The bone morphogenetic proteins (BMPs) belong to the transforming growth factor (TGF)-β superfamily, which also comprises the TGF-βs, activins, nodal, inhibins and myostatin. While BMPs were first discovered because of their ability to promote endochondral bone growth, hence the name, BMP action is now known to contribute to several crucial biological processes throughout . . .

     

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