New tricks with old dogs: computational identification and experimental validation of new mirna-mrna regulation in hipsc-cms

HIGHLIGHTS

  • who: Maja Bencun and collaborators from the University Hospital Heidelberg, Heidelberg, Germany have published the research work: New Tricks with Old Dogs: Computational Identification and Experimental Validation of New miRNA-mRNA Regulation in hiPSC-CMs, in the Journal: Biomedicines 2022, 10, 391. of 07/01/2018
  • what: The authors show by validation that the approach discriminates true from false miRNA target predictions. The authors provide here an overview and catalogue of dynamically regulated miRNAs and their negatively associated mRNA targets during cardiac differentiation and β-adrenergic stimulation. The experiments show that exogenous transfection of the studied . . .

     

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