Genetic and epigenetic pathogenesis of acromegaly

HIGHLIGHTS

  • who: Masaaki Yamamoto and Yutaka Takahashi from the Division of Diabetes and Endocrinology, Kobe University Graduate School of Medicine, Kobe, Japan have published the article: Genetic and Epigenetic Pathogenesis of Acromegaly, in the Journal: Cancers 2022, 14, 3861. of /2022/
  • what: Advances in genome analysis methods have led to the identification of several additional novel causative genes to GNAS mutation over the last 20 years.
  • future: Although the MEN1 genotype-phenotype correlation is not clear it is recommended that MEN1 mutation carriers undergo periodic imaging and endocrinological testing to facilitate early cancer detection . . .

     

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